重组人干扰素α-2b栓联合心理行为干预治疗对慢性宫颈炎患者生活质量、睡眠障碍及心理状态的影响

Recombinant human interferon α- Effect of 2b suppository combined with psychological behavior intervention on quality of life, Sleep disorder and psychological status of patients with chronic Cervicitis

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2023, 50(6)
作者
作者单位

西北妇女儿童医院 妇三科 ;

摘要
【摘要】目的:探讨在慢性宫颈炎患者治疗中,选择重组人干扰素α-2b栓联合心理行为干预的价值,并分析该方案对患者生活、睡眠及心理状态的影响。方法:以EXCEL表格统计2021年1月~2022年10月范围内确诊为慢性宫颈炎的150例患者研究,以随机数字表法分2组,一组接受重组人干扰素α-2b栓治疗(对照组),一组接受重组人干扰素α-2b栓+心理行为干预治疗(观察组)。统计治疗后临床疗效,并就治疗前后生活质量、睡眠状态、心理状态、炎症因子水平进行对比。结果:较对照组而言,观察组75例患者经联合治疗后统计的临床疗效升高(P<0.05);观察组统计的睡眠质量评分、焦虑及抑郁评分下降(P<0.05);观察组统计的生活质量评分升高(P<0.05);观察组统计的IL-6、CRP降低(P<0.05)。结论:在慢性宫颈炎治疗中选择重组人干扰素α-2b栓联合心理行为干预措施可改善其心理状态,减轻疾病对患者睡眠质量的影响,且通过控制机体炎症因子水平,可避免后期疾病反复发作,影响患者生活质量。
Abstract
[Abstract] Objective: To explore the choice of recombinant human interferon in the treatment of chronic Cervicitis patients α- The value of 2b suppository combined with psychological and behavioral intervention, and the impact of this plan on patients life, sleep, and psychological status. Methods: 150 patients with chronic Cervicitis diagnosed from January 2021 to October 2022 were studied with EXCEL table. They were randomly divided into two groups, one receiving recombinant human interferon α- 2b suppository treatment (control group), one group receiving recombinant human interferon α- 2b suppository+psychological and behavioral intervention treatment (observation group). Calculate the clinical efficacy after treatment and compare the quality of life, sleep status, psychological state, and levels of inflammatory factors before and after treatment. Result: Compared with the control group, the clinical efficacy of 75 patients in the observation group increased after combined treatment (P<0.05); The sleep quality score, anxiety and depression score of the observation group decreased (P<0.05); The quality of life score of the observation group increased (P<0.05); The IL-6 and CRP levels in the observation group decreased (P<0.05). Conclusion: Recombinant human interferon should be selected in the treatment of chronic Cervicitis α- The combination of 2b suppository and psychological behavioral intervention measures can improve their psychological state, reduce the impact of the disease on the patients sleep quality, and by controlling the level of inflammatory factors in the body, can avoid recurrent disease attacks in the later stage, which affects the patients quality of life.
关键词
关键词:重组人干扰素α-2b栓;心理行为干预;慢性宫颈炎;生活质量;睡眠障碍;心理状态
KeyWord
Keywords: recombinant human interferon α- 2b bolt; Psychological and behavioral intervention; Chronic Cervicitis; Quality of life; Sleep disorder; Psychological state
基金项目
页码 1458-1460
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袁淼*. 重组人干扰素α-2b栓联合心理行为干预治疗对慢性宫颈炎患者生活质量、睡眠障碍及心理状态的影响 [J]. 国际精神病学杂志. 2023; 50; (6). 1458 - 1460.

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