Journal of International Psychiatry

[Abstract] Objective: To explore the value of dexamethasone combined with psychological intervention in the process of protecting the fetus in patients with threatened miscarriage. Methods: A study was conducted on 80 patients diagnosed with threatened miscarriage in our hospital from February 2020 to October 2022 using an Excel table. The study was randomly divided into two groups: 40 patients treated with dexamethasone were included in the control group, and 40 patients treated with dexamethasone and psychological intervention were included in the observation group. Calculate the clinical efficacy and incidence of adverse reactions after treatment, and evaluate the clinical indicators, psychological status, and improvement time of clinical symptoms before and after treatment. Results: The clinical efficacy of 40 patients in the observation group treated with dexamethasone and psychological intervention was 97.50%, which was higher than that of the control group (P<0.05); The incidence of adverse reactions in the observation group was not statistically significant compared to the control group (P>0.05); Observation group statistics of progesterone, estradiol β- HCG was higher than that of the control group (P<0.05); The SDS and SAS scores of the observation group were lower than those of the control group (P<0.05); The improvement time of symptoms such as low back pain, lower abdominal pain, and vaginal bleeding in the observation group was shorter than that in the control group (P<0.05). Conclusion: The use of dexamethasone combined with psychological intervention in the treatment of threatened miscarriage patients can achieve ideal value, while alleviating the negative emotions caused by the disease and avoiding the mutual impact of the two on the effectiveness of fetal protection.

Keywords: Dextrogestrel; Progesterone; Threatened miscarriage; Fetal protection; Psychological state; Progesterone; Estradiol