| Abstract |
[Abstract] Objective To investigate the relationship between cognitive impairment (CI) and depression and MRI white matter in patients with cerebral infarction. Methods One hundred and four patients with cerebral infarction from April 2021 to February 2023 were included in this study. All patients were screened for cognitive function and depression using the Montreal Assessment Scale (MoCA) and Hamilton Self-Rating Inventory of Depression (HAMD), respectively. They were divided into CI and non-CI groups as well as depression and non-depression groups according to the screening results. All patients underwent cranial MRI examination, and the modified Schehens scale was used to compare and correlate the brain white matter osteoporosis in the occipital, frontal, temporal, parietal, thalamic and cerebellar focus areas and between-group comparisons. All patients underwent cranial MRI examinations, and the modified Schehens scale was used to compare and correlate the white matter sparing in the occipital, frontal, temporal, parietal, thalamic, midbrain and cerebellar areas. Results 104 patients with cerebral infarction were screened for CI in 35 cases and depression in 30 cases. frontal, temporal and parietal Schehens scores were significantly higher in the CI group than in the non-CI group (p<0.05). The differences in the remaining sites were not significant (P>0.05). The frontal Schehens score was significantly higher in the depressed group than in the non-depressed group (P<0.05). The remaining sites were not significantly different (P>0.05). frontal, temporal, and parietal Schehens scores were negatively correlated in the CI group, and HAMD scores were positively correlated with frontal Schehens scores in the depressed group (P<0.05). Conclusion Patients with cerebral infarction have a higher incidence of CI and depression, where CI may be associated with white matter sparing in the frontal, temporal and parietal lobes, and depression may be associated with frontal lobe white matter sparing.
|