| Abstract |
Objective To observe the effect of palliative medical intervention on patients with advanced Alzheimers disease. Methods Sixty patients with advanced Alzheimers disease admitted from January 2021 to December 2022 were randomly divided into an observation group and a control group, with 30 patients in each group. Both groups received routine medical treatment, while the observation group received palliative care on this basis. Compare the two groups of severe impairment scale (SIB), activity of daily living scale (ADL), global deterioration scale (GDS), neuropsychiatric inventory questionnaire (NPI), and Chinese version of pain assessment in advanced dementia scale C-PAINAD before and after intervention, Quality of Life in Late Stage Dementia Scale (QUALIDS) and Zarit Caregiver Burden Scale (ZBI) for patients with advanced dementia. Results After the intervention, there was no statistically significant difference in SIB, ADL, and GDS scores between the observation group and the control group (P>0.05). After intervention, the NPI score of the observer was lower than that of the control group, and the difference was statistically significant (P<0.05). After intervention, the C-PAINAD, QUALIDS, and ZBI scores of the observation group were lower than those of the control group, and the difference was statistically significant (P<0.01). Conclusion Although palliative medicine cannot improve cognitive function and daily living ability of patients with advanced Alzheimers disease, it can improve their mental and behavioral symptoms, significantly improve physical pain, improve quality of life, and reduce caregiver burden.
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