Journal of International Psychiatry

【Abstract】Objective To analyze the association between cognitive function and sleep in adolescent depressive disorder patients with non-suicidal self-injury (NSSI) b ehavior. Methods A total of 100 patients with adolescent depressive disorder who attended our outpatient clinic from December 2021 to January 2023 were selected and divided into NSSI and non-NSSI groups based on the presence or absence of NSSI behaviors; the same scales and tests were evaluated to individuals in both groups, and general information was compared using the self-made clinical characteristics information table; the degree of depression was assessed using the Hamilton Depression Inventory (HAMD-17); the degree of depression was assessed using the Pittsburgh Sleep Quality Index Inventory (PSQI); cognitive function was assessed by the Chinese Brief Neurocognitive Test (C-BCT); sleep was assessed by the Pittsburgh Sleep Quality Index (PSQI); the differences in the scores of relevant scales and tests between the two groups were compared, and the correlation between cognitive function and sleep in the NSSI group was analyzed. Results The differences in general information between the two groups were not statistically significant; HAMD-17 and PSQI scores were higher in the NSSI group than in the non-NSSI group, and C-BCT test score scores were lower in the NSSI group than in the non-NSSI group (p < 0. 05). Pearson correlation analysis showed that information processing speed scores were negatively correlated with sleep duration and daytime dysfunction scores, attention scores were negatively correlated with sleep duration scores, working memory scores were negatively correlated with sleep duration, habitual sleep efficiency, and sleep disturbances scores, and comprehensive abilities with executive function scores were negatively correlated with sleep quality, sleep duration, habitual sleep efficiency, and sleep disturbances scores. Multiple linear regression analysis showed that daytime dysfunction had a significant effect on information processing speed; sleep duration had a significant effect on attention, working memory, and comprehensive abilities with executive function; sleep disturbance had a significant effect on working memory; and sleep quality had a significant effect on comprehensive abilities with executive function. Conclusion Cognitive function and sleep status were more severely impaired in adolescents of depressive disorders with NSSI behaviors, and cognitive function was correlated with sleep status, with daytime dysfunction, sleep duration, sleep disturbance and sleep quality as influencing factors of cognitive function.

Non-suicidal self-injury; Depressive disorder; Cognitive function; Sleep