Journal of International Psychiatry

Abstract Objective: To investigate the clinical effect of the application of group-cognitive behavioral therapy (G-CBT) before modified electroconvulsive therapy in patients with bipolar affective disorder and childhood trauma. Methods: 100 patients with BAD and childhood trauma who were treated in our hospital were selected, and randomly divided into control group and observation group, 50 cases in each group. The control group was treated with MECT, and the observation group was treated with G-CBT combined with MECT, the clinical effects of the two groups were compared. Results: After G-CBT treatment, each dimensions and total scores of Internalized stigma of mental illness scale were significantly lower while treatment compliance was significantly better in the observation group than the control group (P<0.05); besides Hamilton Depression Scale-17 , Young manic rating scale and clinical global impression scale-severity of illness were significantly lower while correct rates of facial emotion recognition including happy, sad, angry, shock (P<0.05). Conclusion: Combining G-CBT on the basis of MECT in the treatment of BAD patients with childhood trauma can effectively improve the treatment compliance, which was beneficial for the improvement of mental status and emotion recognition ability.

Key words：Childhood trauma experience; Bipolar affective disorder; Group cognitive behavior therapy; Modified electroconvulsive therapy; Oxidative stress; Glucose and lipid metabolism; Emotional cognition