International Journal of Medicine and Data

Objective To observe the clinical effect of bronchoalveolar lavage combined with oral roxithromycin in the treatment of bronchiectasis complicated with pulmonary infection. Methods A total of 40 patients with bronchiectasis complicated with pulmonary infection who were admitted to our hospital from October 2020 to October 2021 were selected and randomly divided into the control group and the observation group, 20 cases in each. The patients in the control group were treated with roxithromycin antibiotics. The observation group was given bronchoalveolar lavage combined with oral roxithromycin treatment on the basis of conventional treatment; after 1 month and 3 months of treatment, the clinical total effective rate, duration of clinical symptoms disappearance, PaCO2 in patients with bronchiectasis in the two groups were observed respectively. and PaO2 indicator data. Results After three months of treatment, the total clinical effective rate of the observation group was 95%, and that of the control group was 85%; The time was significantly shorter than that in the control group; after treatment, PaCO2 decreased and PaO2 increased in both groups, but the intensity of changes in the treatment group was greater; WBC, N%, hs-CRP, and PCT in the two groups after treatment were lower than those before treatment, The WBC, N%, hs-CRP and PCT of the observation group after treatment were lower than those before treatment and the control group. Conclusion Taking roxithromycin orally combined with bronchoalveolar lavage has a good therapeutic rate, the symptom disappearance time is significantly shortened, and the blood gas indexes change more than the observation group, with high safety and suitable for promotion.

Bronchoalveolar lavage; Roxithromycin; Bronchiectasis; Pulmonary infection; Clinical efficacy