International Journal of Clinical Research

Objective To explore the predictive value of inflammatory parameters in the peripheral blood before transplantation for IVF outcome in patients with normal ovarian reserve undergoing GnRH antagonist cycles. Methods A retrospective analysis the clinical data including 168 women with normal ovarian reserve undergoing the GnRH antagonist cycles. They were divided into pregnancy group (n=83) and non-pregnancy group (n=85) . The inflammatory parameters in the peripheral blood were compared between the two groups. Logistic regression analysis was used to study the predictive value of each parameters on pregnancy outcome. Results The NLR, PLR and SII of the non-pregnancy group were higher than that of the pregnancy group, (P＜0.05). Logistic regression analysis was found that SII was independent factors for pregnancy outcome in patients with IVF undergoing GnRH antagonist cycles. Conclusions For the patients with normal ovarian reserve undergoing GnRH antagonist cycles, SII has poor predictive value for adverse pregnancy outcome.

Fertilization in vitro; Embryo transfer; Peripheral blood inflammatory parameter; Pregnancy outcome