双腔在线血液透析滤过(PHF)在终末期肾脏病患者中的应用效果分析

Analysis of the effect of bipolar online hemodialysis filtration (PHF) in end-stage renal disease patients

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DOI 10.12208/j.ijnr.20240349
刊名
International Journal of Nursing Research
年,卷(期) 2024, 6(10)
作者
作者单位

重庆市荣昌区人民医院 重庆 ;

摘要
分析终末期肾脏病患者提供双腔在线血液透析滤过治疗,明确其治疗效果。方法 回顾性分析我我院收治的40例终末期肾脏病患者进行研究,所有患者均提供双腔在线血液透析滤过治疗,分析患者治疗前后主要评价指标包括尿素清除率、肌酐清除率、β2-微球蛋白清除率、甲状旁腺激素、血红蛋白、IL-6、C反应蛋白、前白蛋白,钙离子,磷离子等,以评估PHF对尿毒症毒素的清除效果。同时,观察患者的生活质量、并发症发生率及生存分析。结果 该40例患者通过双腔在线血液透析滤过干预后,可以提升患者的尿素清除率,提升患者的肌酐清除率、β2-微球蛋白清除率,p<0.05,分析患者的甲状腺膀激素、血红蛋白、IL-6、C反应蛋白、前白蛋白以及钙离子、磷离子均得到有效的改善,p<0.05,评估患者的生活质量明显得到提升,患者的并发症发生率下降,PHF对尿毒症毒素的清除效果得到提升。结论 对终末期肾脏病患者中通过双腔在线血液透析滤过模式,可以改善患者的临床症状,提升其生活质量,改善相关指标,值得提倡。
Abstract
Objective To analyze the treatment of end-stage renal disease patients with double-cavity online hemodialysis filter fruit and determine its therapeutic effect. Methods Retrospective analysis was performed on 40 patients with end-stage renal disease treated in our hospital. All patients were provided with double-cavity online hemodialysis filtration treatment. The main evaluation indexes of patients before and after treatment were analyzed, including urea clearance, creatinine clearance, β2-microglobulin clearance, parathyroid hormone, hemoglobin, IL-6, C-reactive protein, prealbumin. Calcium ions, phosphorus ions, etc., to evaluate the clearance effect of PHF on uremic toxins. Meanwhile, the quality of life, complication rate and survival of patients were observed. Results After the intervention of dual-cavity online hemodidialysis in 40 patients, the urea clearance rate, creatinine clearance and β2-microglobulin clearance of the patients could be improved, p<0.05, and the thyroid hormone, hemoglobin, IL-6, C-reactive protein, prealbumin, calcium ion and phosphorus ion of the patients were effectively improved. p<0.05, the quality of life of the assessed patients was significantly improved, the incidence of complications was decreased, and the clearance effect of PHF on uremic toxin was improved. Conclusion In patients with end-stage renal disease, online hemodialysis with double chest can improve the clinical symptoms, improve the quality of life and improve the related indicators, which is worth advocating.
关键词
双腔在线;血液透析滤过;终末期肾脏病;应用效果
KeyWord
Bipolar Online; Hemodialysis Filtration; End-Stage Renal Disease; Application Effects
基金项目
页码 131-134
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吕洪玉,罗艳*. 双腔在线血液透析滤过(PHF)在终末期肾脏病患者中的应用效果分析 [J]. 国际护理学研究. 2024; 6; (10). 131 - 134.

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