International Journal of Medicine and Data

Objective To analyze the clinical effect of combined use of lumbrokinase and Tongxinluo in elderly patients with cerebral infarction with severe cerebral vascular stenosis. Methods The control group was treated with aspirin combined with rosuvastatin, and the observation group was treated with lumbrokinase combined with Tongxinluo on this basis. The improvement of the degree of vascular stenosis, the score of the nervous system and the changes of related indicators were compared between the two groups. Results The improvement of the degree of vascular stenosis in the observation group was better than that in the control group, and there was a significant difference between the two groups (P<0.05). 0.05). The plasma D-dimer and high-sensitivity C-reactive protein-related indexes of the observation group were better than those of the control group, with significant difference (P<0.05). The effective rate of treatment in the observation group was higher than that in the control group, and the incidence of adverse reactions was lower than that in the control group, with significant differences (P<0.05). Conclusion Lumbrokinase combined with Tongxinluo therapy has a good therapeutic effect on elderly patients with cerebral infarction with severe cerebral vascular stenosis. After treatment, the incidence of acute cerebrovascular disease in patients is reduced, the degree of improvement in vascular stenosis is good, and the thrombolytic effect of patients is improved. Good, the self-care ability has been significantly improved, and the quality of life has improved. After treatment, the patients plaque formation and the secretion of inflammatory mediators of vascular stenosis improved, which can be promoted.

Severe cerebral vascular stenosis; Senile cerebral infarction; Lumbrokinase; Tongxinluo