International Journal of Clinical Research

Objective To explore the impact of neonatal pneumonia and neonatal hyperbilirubinemia on thyroid function in NICU children. Methods According to different disease types, the patients were divided into neonatal pneumonia group and neonatal hyperbilirubinemia group. The neonatal pneumonia group was further divided into neonatal pneumonia without respiratory distress group and neonatal pneumonia with respiratory distress group. Different disease types were compared. Thyroid function. Results The levels of FT4 and FT3 in the neonatal pneumonia combined with respiratory distress group were lower than those in the neonatal pneumonia without respiratory distress group and the neonatal hyperbilirubinemia group, and the difference was significant (P <0.001); the three groups of diseases had higher thyroid-stimulating effects. There was no significant difference in protein levels (P >0.05). However, the three groups of diseases were combined with mild and severe congenital subclinical hypothyroidism, and the difference was not statistically significant (P >0.05). Conclusion In neonatal pneumonia without respiratory distress, neonatal pneumonia with respiratory distress, and neonatal hyperbilirubinemia, FT4 and FT3 show a downward trend as the condition worsens. The presence of the above diseases in neonates in the NICU may affect the monitoring of neonatal thyroid function, and thyroid function should be monitored in a timely manner to guide treatment.

Neonatal pneumonia; Neonatal respiratory distress syndrome; Neonatal hyperbilirubinemia; Thyroid hormone