International Journal of Clinical Research

Objective To analyze the clinical efficacy of nasal high-flow oxygen therapy in the treatment of acute respiratory failure. Methods A retrospective analysis was conducted on the clinical data of 60 patients with acute respiratory failure who were received and treated in our hospital from June 2023 to June 2024. According to the differences in treatment methods, they were divided into a reference group and an experimental group, with 30 cases in each group. The reference group was treated with non-invasive positive pressure ventilation, and the experimental group was treated with nasal high-flow oxygen therapy. The respiratory frequency, arterial blood gas indicators, ventilation time, organ incision or intubation rate, and complication rate were compared between the two groups 24 hours after treatment. Results Compared with the reference group, the respiratory frequency and arterial blood gas indicators of the experimental group were significantly better (P<0.05); the ventilation time of the experimental group was shorter than that of the reference group, and the tracheotomy or intubation rate was significantly lower than that of the reference group. The incidence of complications in the reference group (P<0.05); the experimental group was significantly lower (P<0.05). Conclusion Nasal high-flow oxygen therapy has significant clinical effects in the treatment of acute respiratory failure. It can effectively improve patients respiratory function and optimize arterial blood gas levels, shorten ventilation time, reduce tracheotomy or intubation rates and the incidence of complications.

Acute respiratory failure; Nasal high-flow oxygen therapy; Non-invasive positive pressure ventilation; Respiratory frequency; Arterial blood gas indicators