International Journal of Clinical Research

Objective To explore the research on Bushen Huoxue Decoction combined with cyclophosphamide in the treatment of refractory nephrotic syndrome. Methods 60 patients with refractory nephrotic syndrome admitted to our hospital from January 2023 to January 2024 were selected as research subjects and randomly divided into two groups. The control group was treated with cyclophosphamide, and the observation group was treated with cyclophosphamide. On the basis of combined treatment with Bushen Huoxue Decoction, the total effective rate, biochemical indicators, incidence of adverse reactions and TCM symptom scores of the two groups were compared. Results The total effective rate of treatment in the observation group was better than that in the control group, the incidence of adverse reactions in the observation group was lower than that in the control group, the TCM symptom score in the observation group was lower than that in the control group, and the biochemical indicators in the observation group were better than those in the control group (P<0.05). The data were statistically significant significance. Conclusion Bushen Huoxue Decoction combined with cyclophosphamide has a significant effect in the treatment of refractory nephrotic syndrome, improves clinical efficacy and promotes recovery, and has high clinical research and application value.

Bushen Huoxue Decoction; Cyclophosphamide; Refractory nephrotic syndrome; Enhancing immune function