他克莫司单药治疗特发性膜性肾病的疗效观察

Therapeutic effect of tacrolimus on idiopathic membranous nephropathy

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DOI 10.12208/j. ijim.20220034
刊名
International Journal of Internal Medicine
年,卷(期) 2022, 3(2)
作者
作者单位

临沂市第三人民医院内分泌与肾内科 山东临沂 ;

摘要
分析单用他克莫司治疗成人特发性膜性肾病(IMN)的价值。方法 选取2017年6月至2019年6月临沂市第三人民医院肾内科IMN患者,共60例。随机分组,分析组(n=32)单用他克莫司(TAC)治疗,对照组(n=28)联合小剂量糖皮质激素。结果 分析组28例患者(87.5%)缓解,对照组24例患者(85.7%)缓解,P>0.05。不良反应差异显著,P<0.05)。结论 单用他克莫司方案治疗IMN的缓解率与联合治疗相当,但不良事件发生率低,减少了副作用。
Abstract
Objective To analyze the value of adult-based membrane nephropathy (IMN) in the analysis of the analysis. Methods selected 60 patients with IMN from June 2017 to June 2019, with a total of 60 patients with IMN. Random grouping, analysis group (n=32) alone was treated with other TAC (TAC), and the control group (n=28) combined with small dose of glucocorticoids. Results 28 patients (87.5%) were relieved, and 24 patients (85.7%) were relieved by the control group, P>0.05. The difference in adverse reactions is significant, P<0.05). Conclusion The relief rate of the IMN using his Kemodos solution is equivalent to combined therapy, but the incidence of adverse events is low, which reduces side effects.
关键词
特发性膜性肾病;他克莫司;糖皮质激素
KeyWord
Idiopathic membranous nephropathy; Tacrolimus; Glucocorticoid
基金项目
页码 19-21
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赵谭,黄秋静,赵振*. 他克莫司单药治疗特发性膜性肾病的疗效观察 [J]. 国际内科前沿杂志. 2022; 3; (2). 19 - 21.

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