International Journal of Nursing Research

The first antibiotic in clinical application is penicillin, which has a strong anti-staphylococcus aureus effect. Since the 1940s, when penicillin was used in clinic, clinical research and development of antibacterial drugs have been intensified, and various new antibacterial drugs are widely used in clinical treatment of various diseases. Although these drugs have reduced the mortality rate of patients with infectious diseases (pneumonia, tuberculosis, etc.), there is a widespread problem of abuse of antibacterial drugs. As a result, some pathogenic bacteria become resistant to some antimicrobial drugs, and a variety of Multi-drug resistant bacteria (MDRO) are generated, of which methicillin-resistant Staphylococcus aureus is the earliest MDRO found in the clinic. MDRO is the main cause of hospitalization outbreak, once infected with MDRO, it will significantly increase the difficulty of treatment and increase the mortality of patients. Therefore, it is of great clinical value to study the status quo and prevention and control measures of hospital feeling caused by MDRO.

Multi-drug resistant bacteria; Hospital infection; Prevention and control measures