International Research in Chinese Medicine

Objective In recent years, the marine ecosystem has been continuously damaged, and most of the sunscreen lotions on the market contain chemical ingredients that pollute the marine environment. In addition, ordinary sunscreen lotions have the disadvantages of limited protection against ultraviolet wavelengths, short duration of sun protection and skin irritation; Based on this, this project utilizes the traditional Chinese medicine phellodendron, which has the ability to absorb ultraviolet rays, to synthesize mild and skin-friendly traditional Chinese medicine liposomes and combines them with AL-PDA/TiO2 composite nanoparticles to prepare a green and healthy physical and chemical dual-acting anti-ultraviolet sunscreen lotion with no added flavors and preservatives. It is hoped that this will provide new ideas for the preparation of sunscreen lotions using plant activities. Methods The active ingredients of Phellodendron Bark were extracted by Soxhlet extraction and made into Phellodendron Bark liposomes as chemical anti-UV agents by thin film dispersion method. Subsequently, we modified dopamine on the surface of lignin and synthesized AL-PDA/TiO2 as a physical anti-ultraviolet agent by ultrasonic chemical method. Finally, orthogonal experiments, quality evaluation and other experiments were used to complete the formulation design of the physical and chemical double-effect anti-UV sunscreen lotion. Results Through the characterization of the materials and the multi-dimensional evaluation and analysis of the quality, efficacy and sensory of the sunscreen lotion, it was concluded in this experiment that the experimental sunscreen lotion with 18% of cypress sunscreen liposome addition and 15% of AL-PDA/TiO2 composite nanoparticle addition had good feeling, appearance, and UV-resistant ability, which were the best formulations for this experimental sunscreen lotion. Conclusion Experimentally prepared sunscreen milk after a number of tests have reached satisfactory results, and the preparation of simple raw materials, low price, good sunscreen effect, has a good feasibility as well as application prospects, is expected to become a new system of sunscreen milk on the market.

Sunscreen; Liposome; Lignin; TiO2; Phellodendron