人乳头瘤病毒DNA(HPV-DNA)、液基薄层细胞学检测(TCT)在宫颈癌筛查中的应用价值观察

Application value of human papillomavirus DNA (HPV-DNA) and liquid-based thin layer cytology(TCT) in cervical cancer screening

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DOI 10.12208/j. ijog.20220019
刊名
International Journal of Obstetrics and Gynecology
年,卷(期) 2022, 2(1)
作者
作者单位

新兴妇幼保建计划生育服务中心妇产科 广东云浮 ;

摘要
探讨宫颈癌筛查中,应用人乳头瘤病毒DNA(HPV-DNA)检测、液基薄层细胞学检测(TCT)的筛查效果。方法 选取200例疑似宫颈癌的患者为研究对象,患者均采取HPV-DNA、TCT检测,以阴道镜下活检作为金标准,对比单纯与联合检测在宫颈癌筛查中的价值。结果 200例宫颈癌患者,经活检阳性78例,而经单纯HPV-DNA检测符合率为84.00%,单纯TCT符合率为88.00%,HPV-DNA联合TCT符合率为98.00%,联合检测的符合率明显高于单一检测(P<0.05)。结论 在宫颈癌筛查中,应用HPV-DNA联合TCT检测具有极高的应用价值,值得推广。
Abstract
Objective To investigate the screening effect of human papillomavirus DNA (HPV-DNA) and liquid-based thin layer cytology (TCT) in cervical cancer screening. Methods A total of 200 patients with suspected cervical cancer were enrolled. The patients were treated with HPV-DNA and TCT. The colposcopy biopsy was used as the gold standard. The value of simple and combined detection in cervical cancer screening was compared. Results Of the 200 patients with cervical cancer, 78 were positive by biopsy, and the coincidence rate of HPV-DNA was 84.00%. The coincidence rate of TCT was 88.00%. The coincidence rate of HPV-DNA combined with TCT was 98.00%. The rate was significantly higher than the single test (P < 0.05). Conclusion In the screening of cervical cancer, the application of HPV-DNA combined with TCT detection has extremely high application value and is worthy of promotion.
关键词
人乳头瘤病毒DNA;液基薄层细胞学检测;宫颈癌筛查;应用价值
KeyWord
Human papillomavirus DNA; Liquid-based thin layer cytology; Cervical cancer screening; Application value
基金项目
页码 64-67
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李海英*. 人乳头瘤病毒DNA(HPV-DNA)、液基薄层细胞学检测(TCT)在宫颈癌筛查中的应用价值观察 [J]. 国际妇产科研究. 2022; 2; (1). 64 - 67.

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