铁蛋白在噬血细胞综合征中的应用-国际临床研究杂志-CSCIED科技核心评价数据库-手机版

铁蛋白在噬血细胞综合征中的应用

Application of ferritin in hemophagocytic syndrome

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DOI	10.12208/j.ijcr.20220194
刊名	国际临床研究杂志 International Journal of Clinical Research
年，卷(期)	2022, 6(5)
作者	陈岚,李叶琼,冶秀鹏*,
作者单位	宁夏医科大学附属第三临床学院（宁夏回族自治区人民医院）宁夏银川 ;
摘要	噬血细胞综合征又称噬血细胞性淋巴组织细胞增生症（hemophagocytic lymphohistocytosis, HLH），是由遗传性或获得性免疫调节异常导致的过度炎症反应综合征，发病率低，病死率高，进展迅速，严重可危及生命。其诊断的非特异性特点，使其易与众多疾病混淆，从而延误诊断和治疗。血清铁蛋白通常和HLH疾病活动度呈正相关，在HLH的早期诊断和治疗监测中有重要意义。本文着重对HLH的诊断、实验室检查，尤其铁蛋白应用及治疗新进展进行综述。
Abstract	Hemophagocytic syndrome, also known as hemophagocytic lymphohistocytosis (HLH), which is an excessive inflammatory response syndrome caused by genetic or acquired immune regulation. It has low incidence rate, high mortality rate, and rapid progress, which can seriously endanger life. It is easy to be confused bacause of nonspecific diagnosis, thus delaying the diagnosis and treatment. Serum ferritin is usually positively correlated with HLH disease activity, which is of great significance in the early diagnosis, treatment and monitoring of HLH. This paper focuses on review the diagnosis and laboratory examination of HLH, especially the application of ferritin and advance in treatment in HLH.
关键词	噬血细胞综合征；实验室检查；铁蛋白；治疗
KeyWord	Hemophagocytic syndrome; Laboratory examination; Ferritin; Treatment
基金项目
页码	7-11

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引用本文

陈岚,李叶琼,冶秀鹏*. 铁蛋白在噬血细胞综合征中的应用 [J]. 国际临床研究杂志. 2022; 6; (5). 7 - 11.

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