有关氨糖葡萄糖硫酸钾盐等原料增加动物骨密度的实验及机制研究
Experimental and mechanism study on the increase of animal bone mineral density by raw materials such as aminosaccharide, glucose and potassium sulfate
ES评分 0
| DOI |
10.12208/j.imrf.20240004 |
| 刊名 |
International Medical Research Frontier
|
| 年,卷(期) |
2024, 8(1) |
| 作者 |
|
| 作者单位 |
1 齐鲁工业大学(山东省科学院)山东省分析测试中心 山东济南 ; 2 中国营养学会 北京 ; 3 广东药科大学 广东广州 ; 4 唐山市健康管理师协会 河北唐山 ;
|
| 摘要 |
本研究探讨了氨糖葡萄糖硫酸钾盐、碳酸钙、硫酸软骨素钠和酪蛋白磷酸肽等原料组合对动物骨密度的影响。研究表明,这些原料通过增强肠道中钙、磷等矿物质的吸收效率,有效地将更多矿物质运输到骨骼中,参与到骨的形成和矿化过程中,从而显著增加骨矿含量。此外,这种原料组合刺激软骨细胞合成蛋白多糖和胶原蛋白,加速软骨基质的合成、修复和再生,增强软骨的机械强度和功能。研究还发现,该组合能够共同作用于骨骼的整体生长和修复,有效抑制骨吸收,促进骨密度的增加。通过对动物模型的实验验证,结果显示氨糖软骨素钙胶囊能显著提高骨密度,表明其具有良好的临床应用潜力。
|
| Abstract |
This study studied the effects of the combination of ammonium glucose potassium sulfate, calcium carbonate, chondroitin sulfate sodium and casein phosphopeptide on animal bone mineral density. Studies have shown that these raw materials effectively transport more minerals to bone by enhancing the absorption efficiency of minerals such as calcium and phosphorus in the gut, and participate in the process of bone formation and mineralization, thus significantly increasing bone mineral content. In addition, this raw material combination stimulates the synthesis of proteoglycan and collagen by chondrocytes, accelerates the synthesis, repair and regeneration of cartilage matrix, and enhances the mechanical strength and function of cartilage. The study also found that the combination can work together on the overall growth and repair of bone, effectively inhibit bone resorption, and promote the increase of bone density. Through the experimental verification of animal models, the results showed that aminochondroitin calcium capsule can significantly improve bone mineral density, indicating that it has good clinical application potential.
|
| 关键词 |
增加骨密度;作用机制;动物实验
|
| KeyWord |
Increase bone mineral density; Mechanism of action; Animal experiment
|
| 基金项目 |
|
| 页码 |
17-20 |
李涛*,郭伟,魏贺敏,朱华.
有关氨糖葡萄糖硫酸钾盐等原料增加动物骨密度的实验及机制研究 [J].
国际医药研究前沿.
2024; 8; (1).
17 - 20.