International Journal of Medicine and Data

Objective To analyze the application value of using cell wax block technique in pathological examination of pleural effusion. Methods Collect the remaining pleural effusion samples from the pathology cell room of our hospital from January to November 2023 after cellular pathology diagnosis. Select 40 cases with visible tumor cells diagnosed and divide them into a reference group (traditional smear technique) and an experimental group (cell wax block technique), with 20 cases in each group. Compare the effectiveness and diagnostic results of the two groups. Results The local smear thickness of the reference group was uneven, with 14 cases showing tumor cells and 6 cases showing no tumor cells, with a diagnostic effective rate of 70.00%. The experimental group had clean slice backgrounds, with 19 cases showing tumor cells and 1 case showing no tumor cells, with a diagnostic effective rate of 95.00%. It can be seen that the diagnostic efficiency of the experimental group is higher than that of the reference group (P<0.05). The classification diagnosis results of immunohistochemistry combined with cell wax block preparation technology showed that adenocarcinoma accounted for 63.15%, while squamous cell carcinoma, small cell carcinoma, malignant mesothelioma, malignant mesothelioma, and other types of tumors all accounted for 5.26%, which cannot be determined as 15.80%. Conclusion The diagnostic effectiveness of using cell wax block technique in pathological examination of pleural effusion is higher than that of traditional smear technique, and it can be preserved for a long time, repeated sectioning, and used for multiple other examinations. This method is worth promoting and optimizing.

Cell wax block technology; Thoracic effusion; Pathological examination; value