International Journal of Clinical Research

Objective To investigate the predictive value of neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), red blood cell to platelet ratio (RPR), red blood cell to lymphocyte ratio (RLR), platelet to lymphocyte ratio (PLR) and other inflammatory markers in upper gastrointestinal bleeding in decompensated cirrhosis . Methods 200 patients with decompensated cirrhosis admitted to the Department of Gastroenterology, the Third Peoples Hospital of Yunnan Province from 2020 to 2023 were selected and divided into bleeding group (100 cases) and non-bleeding group (100 cases) according to the absence of gastrointestinal bleeding. First, the ratios of NLR, LMR, RPR, RLR and PLR were calculated, and the differences of the above 5 inflammatory markers between the bleeding group and the non-bleeding group were compared by the non-parametric test method of two independent samples, and the ROC curve was drawn to screen out the indicators with predictive value for upper gastrointestinal bleeding in decompensated cirrhosis. Result The P value of PLR is (p < 0.061), the P value of NLR is (p < 0.000), the P value of LMR is (p < 0.052), the P value of RPR is (p < 0.091), and the P value of RLR is (p < 0.002). Therefore, the two inflammatory markers of NLR and RLR had predictive value for upper gastrointestinal bleeding in decompensated cirrhosis (P < 0.05). ROC curve analysis showed that the areas under PLR, NLR, LMR, RPR and RLR curves were 0.577, 0.663, 0.580, 0.569 and 0.628, respectively. Therefore, NLR and RLR had higher predictive value for upper gastrointestinal bleeding in decompensated cirrhosis. Conclusion NLR, LMR, RPR, RLR and PLR have predictive value for upper gastrointestinal hemorrhage in decompensated cirrhosis, and NLR and RLR have higher predictive value for upper gastrointestinal hemorrhage in decompensated cirrhosis.

NLR; LMR; RPR; RLR; PLR; Decompensated cirrhosis; Upper gastrointestinal bleeding