International Journal of Clinical Research

Objective: to investigate the clinical efficacy and safety of aspirin and clopidogrel in the treatment of elderly patients with coronary heart disease. Methods: from March 2022 to March 2022,180 elderly patients with coronary heart disease were 2024 in the second peoples Hospital of Yunan County, they were divided into control group (aspirin) and observation group (add-on clopidogrel) according to the treatment mode. The levels of inflammatory factors and the incidence of complications before and after treatment were compared between the two groups. Results: before treatment, there was no significant difference in the levels of inflammatory factors such as IL-6 and CRP between the two IL6 groups (P > 0.05) . After treatment, the inflammatory factors and the probability of complications in the observation group were better than those in the control group (p < 0.05). Conclusion: aspirin and clopidogrel are more effective in the treatment of elderly patients with coronary heart disease, which can reduce the probability of inflammation and improve the therapeutic effect, at the same time, the safety of drug use is also higher, with higher use value.

Coronary heart disease; Aspirin; Clopidogrel