International Journal of Obstetrics and Gynecology

Objective To analyze the prevalence and distribution of cervical cytology (TCT) and human papillomavirus (HPV) in womens health checkup population for three consecutive years from 2020 to 2022, so as to provide a basis for more effective monitoring of cervical cancer prevention and treatment strategies. Methods Cervical secretions from female physical examination patients in Tianjin Grade A Hospital were collected and analyzed by liquid base thin layer cytology (TCT) and human papillomavirus (HPV) molecular detection respectively. Results A total of 18,585 female physical examination subjects were included in the three-year study, of which 17,473 underwent TCT examination, including 3,854 in 2020, 7,402 in 2021, and 6,217 in 2022. The remaining 1,112 were tested for human papillomavirus (HPV) molecules, including 619 in 2021 and 493 in 2022. TCT examination results showed that the three-year average positive rate was 2.507%, and the highest positive rate was 2.905% in 2021. There was a significant difference in the positive rate in three years (*P < 0.05), and the difference between 2020 and 2021 was the most significant (**P < 0.005). The average positive rate of HPV detection was 10.522%, with no significant difference among different years (P > 0.05), and the positive rate in 2021 was 11.309%. In addition, both TCT and HPV-positive detection results showed an increasing trend of age. Conclusion To carry out and strengthen regular and standardized cervical cancer screening is an essential link for effective prevention, timely diagnosis and treatment and even elimination of cervical cancer. We should improve the awareness of cervical cancer screening for women with sexual life, especially women in the age group with high incidence of cervical cancer.

liquid-base thin-layer cytology; Human papillomavirus; Cervical lesions; Cervical cancer; Prevalence rate