International Journal of Clinical Research

Nasopharyal carcinoma is one of the most common head and neck tumors in China. In recent years, with the continuous development and progress of the treatment technology and treatment model, Early nasopharyngeal carcinoma patients can survive by more than 80%in 5 years. However, most patients are in the middle and late stages when diagnosis. Therefore, improving efficacy is an important means to reduce local recurrence and distant metastasis. Circulating tumor cells are tumor cells that detach from the primary tumor and infiltrate into the bloodstream. As a clinical tool that provides real-time key molecular information, they can determine new treatment methods based on individual patient tumor characteristics, avoid the continuation of ineffective treatment, and prevent unnecessary adverse reactions, further strengthening cancer management and treatment. Although liquid biopsy has achieved remarkable results in the field of tumors, there is not abundant research data related to nasopharyngeal carcinoma in China. This article will focus on the latest progress and clinical evidence of liquid biopsy mainly using circulating tumor cells in nasopharyngeal carcinoma, and provide prospects for future development.

Circular tumor cells; Liquid biopsy; Nasopharyal carcinoma; Efficacy monitoring; Prognostic prediction