International Journal of Clinical Research

Objective: To analyze the efficacy of hydrochlorothiazide and irbesartan in the treatment of elderly primary hypertension. Method: 66 elderly patients with primary hypertension were selected from our hospital from January 2022 to January 2023. The random number table method was used as the reference group and experimental group, with 33 cases in each group. The former received treatment with irbesartan, while the latter received treatment with hydrochlorothiazide on this basis. The efficacy of the two groups was compared. Result: The comparison of treatment effectiveness showed that the experimental group was significantly higher (P<0.05). The comparison of blood pressure indicators showed that there was little difference between the two groups before treatment (P>0.05). After treatment, the experimental group showed a significant decrease (P<0.05). The incidence of adverse reactions was significantly lower in the experimental group (P<0.05). Conclusion: Hydrochlorothiazide is more effective than irbesartan alone in the treatment of elderly patients with primary hypertension. It can improve the treatment efficacy, improve blood pressure indicators, and has high safety.

Elderly primary hypertension; Hydrochlorothiazide; Ebeshatanzhi; Effective treatment rate; Blood pressure indicators; Adverse reactions