2013年至2023年肝硬化生物标志物的文献计量和可视化分析

Bibliometric and visual analysis of biomarkers for liver cirrhosis from 2013 to 2023

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DOI 10.12208/j.ijcr.20240007
刊名
International Journal of Clinical Research
年,卷(期) 2024, 8(1)
作者
作者单位

大理大学第二附属医院(云南省第三人民医院) 云南昆明 ;

摘要
本研究通过分析肝硬化生物标志物领域的发文情况、共现、聚类、共被引及可视化分析,探索该领域2013年至2023年的发展状况、研究热点及动态前沿,为该范畴相关人员发展学术研讨提供参考。方法 在Web of Science (WOS)数据库中检索肝硬化生物标志物相关的英文文献(论著或综述)为对象,发表日期限定为2013 年—2023年。运用 CiteSpace 软件对检索到的文献进行可视化分析,并绘制相关可视化图谱。结果 共获得1469 篇文献,结果表明,肝硬化生物标志物范畴文献数量整体呈上升趋向。通过关键词聚类生成 4 个图谱,聚类结果显示研究集中于P53基因、growth factor(生长因子)、long noncoding RNA(长非编码RNA)及miRNA。结论 本研究使用citespace 软件对肝硬化生物标志物可视化分析,初步揭示该领域发展的动态前沿,特别是在长非编码RNA和miRNA这方面的生物标志物用于肝硬化的诊断将会在未来的研究中占有极其重要地位。
Abstract
Objective By analyzing the publication, co-occurrence, clustering, co-citation and visual analysis in the field of liver cirrhosis biomarkers, the study explored the development status, research hotspots and dynamic frontiers of this field from 2013 to 2023, and provided references for the development of academic research for relevant personnel in this field. Methods The English literature on liver cirrhosis biomarkers was searched in the Web of Science (WOS) database, and the publication dates were limited to2013-2023.CiteSpace software was used to visually analyze the retrieved literature and draw the relevant visual maps. Results A total of 1469 literatures were obtained, and the results showed that the number of literatures in the category of liver cirrhosis biomarkers showed an increasing trend. Four maps were generated by keyword clustering, and the clustering results showed that the research focused on P53 gene, growth factor, long noncoding RNA and miRNA. Conclusion In this study, CiteSpace software was used for visual analysis of liver cirrhosis biomarkers, which initially revealed the dynamic frontier of development in this field. In particular, biomarkers in long non-coding RNA and miRNA for the diagnosis of liver cirrhosis will play an extremely important role in future studies.
关键词
肝硬化;生物标志物;Web of Science;CiteSpace;可视化分析
KeyWord
Cirrhosis; Biomarkers; Web of Science; CiteSpace; Visual analysis
基金项目
页码 27-33
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罗江焰,毛孝周,马驰,付新年,马笑盈,王鑫鑫,杨涓,郑盛*. 2013年至2023年肝硬化生物标志物的文献计量和可视化分析 [J]. 国际临床研究杂志. 2024; 8; (1). 27 - 33.

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