International Journal of Clinical Research

Objective To explore the clinical efficacy of self-designed Quzhuo Huayu San in the external treatment of acute gouty arthritis with damp heat obstruction type. Methods Sixty patients with gouty arthritis of damp heat obstruction syndrome admitted to our hospital from January 2023 to January 2024 were selected and divided into XY group and Zn group using a double-blind method, with 30 cases in each group. The XY group and Zn group were treated with conventional Western medicine and self formulated Quzhuo Huayu powder, respectively. Compare the knee joint function (Lysholm score), pain status (VAS score), C-reactive protein, uric acid, knee range of motion, pain index, and degree of deformity between two groups. Results ① Lysholm score and VAS score: There was no significant difference between the two groups before treatment (t = 0.020.099, P > 0.05), but after treatment, the ZN group had higher Lysholm score and lower VAS score (P<0.05); ② C-reactive protein and uric acid: There was no significant difference between the two groups of patients before treatment (P>0.05), and the ZN group was even lower after treatment (P<0.05); ③ Knee joint range of motion, pain index, and degree of deformity: Before treatment, there was no significant difference between the two groups of patients (P>0.05). After treatment, the ZN group of patients had higher knee joint range of motion, lower pain index, and degree of deformity score (P<0.05). Conclusion In the treatment of patients with acute gouty arthritis of damp heat obstruction type, the use of self-designed Quzhuo Huayu San external treatment intervention can effectively improve knee joint function, reduce pain levels, improve inflammatory factor levels, enhance knee joint mobility, and reduce joint deformities. It is worth promoting and implementing.

Self-designed to remove turbidity and remove blood stasis; Acute gouty arthritis; Dampness-heat obstruction type; Clinical efficacy