International Journal of Clinical Research

Diabetes, as a metabolic disease, its main symptom is hyperglycemia. Diabetic retinopathy (DR) is the chronic ocular microvascular inflammation caused by diabetes. The root cause of DR is that the blood vessels in the eye are in a state of hyperglycemia for a long time, leading to REDOX imbalance, oxidative stress and chronic mild inflammatory reaction, etc. Dr is regarded as one of the more serious complications of diabetes. At present, the prevalence of diabetes mellitus (DM) in China continues to increase, while the incidence of DR Continues to rise, and has become the highest blind eye disease in China. The formation process of DR is extremely complex, which is a gradually worsening disease caused by a variety of factors. Although the specific formation principle of DR is not clear at present, relevant studies have pointed out that there is a certain degree of interaction between cytokines and the formation and evolution of DR. In order to deepen the understanding of the influence of cytokines on DR, the correlation between inflammatory index, vascular proliferation-related factors and chemokines and DR will be deeply discussed in this paper, in order to provide a theoretical basis for the study of diabetic retinopathy.

Cytokines; Diabetes; Retinopathy; Research progress