International Journal of Clinical Research

Objective To analyze the therapeutic effect of different localization methods in linear accelerator radiotherapy for advanced esophageal cancer. Methods Patients with advanced esophageal cancer diagnosed in our hospital and treated with linear accelerator emission were studied from December 2022. December to December 2023.December. All 50 cases were divided into two groups according to random number table method, with an average of 25 cases in each group. The two groups were treated with linear accelerator radiotherapy, the control group was treated with conventional barium meal positioning, the observation group was treated with CT simulated positioning, and the therapeutic effect of the two groups was compared. Results The objective response rate and tumor marker level of the observation group were better than those of the control group after linear accelerator radiotherapy with simulated CT positioning, and the differences between the groups were significant (P < 0.05). There was no significant difference in the incidence of adverse events between the two groups (P > 0.05). Conclusion In the treatment of advanced esophageal cancer with linear accelerator radiotherapy, CT simulated localization can further improve clinical efficacy, improve tumor markers, and have good safety guarantee.

Barium meal positioning; CT simulation positioning; Linear accelerator; Advanced esophageal cancer