International Journal of Clinical Research

Objective To analyze the clinical effect of domperidone in the treatment of chronic gastritis. Methods All 96 patients with chronic gastritis diagnosed and treated in our hospital from September 2022 to September 2023 were randomly divided into two groups, with an average of 48 cases in each group. The control group was treated with ranitidine and the observation group was treated with domperidone. The clinical therapeutic effect, inflammatory factor levels and adverse reactions of the two groups were comprehensively evaluated. Results The total effective rate of the observation group was significantly higher than that of the control group (P < 0.05). The levels of CRP, IL-32 and MCP-1 in the observation group were significantly lower than those in the control group after treatment (P < 0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group (P < 0.05). Conclusion Domperidone is more effective in chronic gastritis, which can relieve inflammation and has good safety.

Chronic gastritis; Domperidone; Inflammatory response