International Journal of Clinical Research

Objective To evaluate the CT value of cancellous bone of lumbar spine in the diagnosis of osteoporotic fracture. Methods A total of 24 patients with osteoporotic fractures who underwent routine CT scan in our hospital were prospectively included in the study and assigned as the observation group. In addition, 24 patients with no fracture matching age and BMI were included in the study and set as the control group. CT values of cancellous bone of L1 vertebral body were obtained by single ROI method, and bone mineral density (BMD) T values of L1 vertebral body were obtained by dual-energy X-ray absorptiometry (DXA). The difference of CT value and BMD-T value of L1 vertebra between the two groups was compared and the correlation was analyzed. The value of cancellous bone CT value and BMD-T value in the diagnosis of osteoporotic fracture was analyzed by ROC curve. Results The CT and BMD-T values of L1 vertebra in observation group were significantly lower than those in control group, and the comparison between groups was significant (P < 0.05). CT and BMD-T values of L1 vertebra were positively correlated between the two groups (r=0.739, 0.374, P < 0.05). There was no significant difference between CT and BMD-T values of cancellous bone in the differential diagnosis of osteoporotic fractures (P > 0.05). Conclusion CT values of lumbar cancellous bone can be used in the differential diagnosis of osteoporotic fractures with high sensitivity.

CT value of cancellous bone of lumbar spine; Osteoporosis fracture; Dual-energy X-ray bone densitometer; Bone mineral density T value