International Journal of Clinical Research

Objective To analyze the efficacy of esomeprazole and omeprazole in the treatment of gastric ulcers. Methods 84 patients with gastric ulcers admitted to a hospital from January 2023 to December 2023 were selected as the study subjects. They were randomly divided into a control group and an observation group using a random number table method, with 42 cases in each group. The control group was treated with omeprazole, while the observation group was treated with esomeprazole. The therapeutic effects of the two groups were compared. Results After treatment with emergency esomeprazole, the clinical symptom improvement score, inflammatory factor levels, and incidence of adverse reactions in the observation group were lower than those in the control group, with significant differences between groups (P<0.05). Conclusion Compared to omeprazole, esomeprazole has a better therapeutic effect on gastric ulcers, can effectively improve patient related symptoms, alleviate inflammatory reactions, and is relatively safe.

Esomeprazole; Omeprazole; Gastric ulcer; Inflammatory factors