International Journal of Clinical Research

Objective To observe the curative effect of Linggan Wuwei Jiangxin Decoction in the treatment of chronic bronchitis. Methods 100 patients with chronic bronchitis in the respiratory department of our hospital from February 2020 to February 2023 were retrospectively selected and divided into two groups based on ambroxol hydrochloride treatment Linggan Wuwei Jiangxin Tang group (Linggan Wuwei Jiangxin Tang group) and ambroxol hydrochloride treatment group, with 50 cases each. TCM syndrome score, inflammation index, lung function and blood gas analysis index, immune function, clinical efficacy, occurrence of adverse reactions and symptom disappearance time of the two groups were statistically analyzed. Results The levels of cough, phlegm volume, rales, cold fear score and total score, IL-6, CRP, WBC, FRC and PaCO2 in Linggan Wuwejiangxin Tang group were lower than those in ambroxol hydrochloride treatment group (P<0.05), and the levels of RR, PEF, PaO2, IgA, IgG and IgM were higher than those in ambroxol hydrochloride treatment group (P<0.05). The total effective rate of Linggan WuweiJiangxin Decoction group was 98.00% (49/50) higher than that of ambroxol hydrochloride group (82.00% (41/50) (χ2=7.111, P<0.05). The incidence of adverse reactions in Linggan Wuwei Jiangxin Decoction group was 2.00% (1/50) lower than that in ambroxol hydrochloride group (22.00% (11/50) (χ2=9.470, P<0.05). The disappearance time of sputum, cough, fever and rales in Linggan Wuwei Jiangxin Decoction group was shorter than that in ambroxol hydrochloride group (P<0.05). Conclusion Linggan Wuwei Jiangxin Decoction is effective in treating chronic bronchitis.

Chronic bronchitis; Linggan five-flavor ginger Xin Tang; Ambroxol hydrochloride; TCM syndrome score; Indicators of inflammation; Lung function and blood gas analysis index; Immune function; Adverse reaction