International Journal of Clinical Research

Objective To analyze the clinical effect of tacrolimus combined with low-dose hormone therapy in patients with IgA nephropathy. Methods In this study, 60 cases of IgA nephropathy patients admitted to our hospital were selected, and all cases were divided into observation group and control group according to random number table method, 30 cases in each group. The control group was treated with tacrolimus alone, and the observation group was treated with small-dose hormone therapy. The therapeutic effect of the two groups was compared. Results The improvement time of symptoms in the observation group was significantly shorter than that in the control group, the improvement effect of inflammatory factors and renal function was better than that in the control group, the complication rate was lower than that in the control group, and the total effective rate was higher than that in the control group (P<0.05). Conclusion The combination regimen of tacrolimus and low-dose hormone in IgA nephropathy patients can further improve the clinical treatment effect, improve the clinical symptoms of patients in a short time, reduce the level of inflammatory factors in the body, reduce the occurrence of complications, reduce the degree of renal damage, and improve the effect of disease control.

IgA nephropathy; Tacrolimus; Small doses of hormones; Effect analysis