| Abstract |
[Abstract] Objective To explore the characteristics and significance of resting-state functional magnetic resonance imaging (rs-fMRI) in patients with anxiety disorders. Methods Forty patients with anxiety disorders in our hospital from January 2020 to January 2022 were the subjects of this study, which were set as the observation group, and another 40 healthy physical examination personnel were selected as volunteers, which were set as the control group. 3.0TMRI imager was used for resting-state fMRI imaging, and Matlab2011b platform was used for rs-fMRI data processing, and the brain regions with significant differences in Re Ho values between the two groups were compared. The Self-rating Anxiety Scale (SAS) in patients with anxiety disorders was evaluated, and the correlation between the Re Ho value of abnormal brain regions and the SAS score was analyzed. Results The Re Ho values of the left superior frontal gyrus, left middle frontal gyrus, right inferior frontal gyrus, and right precuneus in the observation group were significantly higher than those in the control group, and the right thalamus, right fusiform gyrus, right middle occipital gyrus, The left middle frontal gyrus was significantly lower than the control group (P<0.05). The left superior frontal gyrus, right inferior frontal gyrus, and right precuneus were positively correlated with the SAS score, while the right thalamus, right fusiform gyrus, and right middle occipital gyrus were negatively correlated with the SAS score (P<0.05). Conclusion The rs-fMRI of patients with anxiety disorder has abnormal activity in multiple brain regions, and the right thalamus and left superior frontal gyrus may be related to the onset and development of anxiety disorder.
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