Journal of International Psychiatry

[Abstract] Objective To explore the effect of mindfulness-based stress reduction therapy on anxiety and depression in patients with gastroesophageal reflux disease. Methods Eighty patients with gastroesophageal reflux disease from August 2020 to January 2022 were selected as the study subjects. They were randomly divided into two groups according the number table method. The patients in the control group received routine nursing care, while the patients in the observation group received mindfulness-based stress reduction therapy on the basis of the control group. The self-rating depression scale (SDS), self-rating anxiety scale (SAS), gastroesophageal reflux disease questionnaire (GERDQ) and gastroesophageal reflux disease health-related quality of life scale (GERD-HRQL) were evaluated in the two groups before and after nursing. Results The SDS and SAS scores of the two groups after nursing were significantly lower than those before nursing, and the observation group after nursing was significantly lower than the control group (P<0.05). After nursing, the GERDQ scores of the two groups were significantly decreased, while the GERD-HRQL scores were significantly increased. After the intervention, the GERDQ scores of the observation group were lower than those of the control group, and the GERD-HRQL scores of the observation group were higher than those of the control group (P<0.05). Conclusion Mindfulness-based decompression therapy can significantly improve anxiety and depression in patients with gastroesophageal reflux disease, play an auxiliary role in relieving gastroesophageal reflux symptoms, and improve related quality of life.

Key words Mindfulness-Based Stress Reduction; Gastroesophageal Reflux Disease; Anxiety; Depression