| Abstract |
[Abstract] Objective To explore the value of MRI in the diagnosis of senile first-episode schizophrenia. Methods From September 2020 to July 2022, 83 elderly first-episode schizophrenics in our hospital were treated as the observation group, and 82 healthy people were selected as the control group at the same time. The parameters of white matter lesions, brain area lesions and gray matter density were compared between the two groups. Results In the observation group, the distance between the anterior horn and the body, the width of the third ventricle, the width of the left and right sylvian cisterns, and the distance between the anterior half of the longitudinal cerebral fissure were lower than those in the control group, and the distance between the trigonal regions was higher than that in the control group (P<0.05); The area of left and right lateral ventricles in the observation group was larger than that in the control group, the length from the horizontal line to the lower margin of the corpus callosum and the length from the midline of the brain were longer than those in the control group, the thickness of the middle segment of the foot of the fornix was lower than that in the control group, and the thickness of the area close to the corpus callosum was higher than that in the control group (P<0.05); The grey matter density of left and right caudate nucleus head, left anterior cerebellar lobe, left posterior cerebellar lobe and bilateral thalamus in the observation group were lower than those in the control group (P<0.05). Conclusion MRI can accurately detect the changes of white matter, brain area lesion parameters and gray matter density data in elderly first-episode schizophrenic patients, so as to preliminarily evaluate the abnormal situation of patients brain lesions, find out the relationship with clinical symptoms, and provide some basis for treatment.
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