重复经颅磁刺激治疗抑郁症快感缺失研究进展

Research advances in repetitive transcranial magnetic stimulation for depression anhedonia

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2023, 50(3)
作者
作者单位

浙江大学医学院附属精神卫生中心/杭州市第七人民医院 ;

摘要
快感缺失是抑郁症的核心症状,是临床治疗的重点和难点。目前一线抗抑郁药物对抑郁症快感缺失效果欠佳,重复经颅磁刺激在抑郁症快感缺失的应用得到重视。间歇性θ脉冲刺激作为一种较新的经颅磁刺激治疗方法受到临床关注,并应用于抑郁症快感缺失的治疗。本文介绍了抑郁症快感缺失的定义、评估和主要神经机制,综述了经颅磁刺激在抑郁症快感缺失的治疗进展。
Abstract
Anhedonia is the core symptom of depression, which is the focus and difficulty of clinical treatment. At present, first-line antidepressant drugs are not effective in depression anhedonia, and the application of repetitive transcranial magnetic stimulation in depression anhedonia has been paid more attention. Intermittent θ pulse stimulation, as a relatively new transcranial magnetic stimulation therapy, has received clinical attention and been applied in the treatment of depression anhedonia. This article introduces the definition, evaluation and main neural mechanism of depression anhedonia, and reviews the progress of transcranial magnetic stimulation in the treatment of depression anhedonia.
关键词
快感缺失;抑郁症;奖赏回路;重复经颅磁刺激;间歇性θ脉冲刺激
KeyWord
anhedonia; depression; reward circuit; rTMS; iTBS
基金项目
页码 388-390
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李冕*. 重复经颅磁刺激治疗抑郁症快感缺失研究进展 [J]. 国际精神病学杂志. 2023; 50; (3). 388 - 390.

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