Journal of International Psychiatry

[Abstract] Objective To explore the anxiety status of peptic ulcer (PU) and its relationship with clinical symptoms. Methods A total of among the inpatients in the Department of Gastroenterology of our hospital, 110 patients with PU on gastroscopy from June 2020 to January 2023 were selected as the study subjects. Hamilton Anxiety Scale (HAMA) was used to assess the anxiety state of patients. The patients with anxiety were set as the anxiety group, and the other patients were set as the control group. The severity of abdominal distension, abdominal pain and belching between the two groups were compared. The l quality of life instruments for chronic diseases- peptic ulcer（QLICD-PU)between the two groups were compared. The correlation between HAMA score, symptom score and quality of life in anxiety group were analyzed. Results There were 40 cases of anxiety in 110 PU patients. The score of abdominal distension, nausea and vomiting, belching, acid regurgitation and total score of symptoms in anxiety group were significantly higher than those in control group (P<0.05). There was no significant difference in abdominal pain and heartburn scores (P>0.05). The body function, psychological function, social function, specific module and total score of QLICD-PU scale in anxiety group were significantly lower than those in control group (P<0.05); The HAMA score of anxiety group was positively correlated with the total score of symptom score, and negatively correlated with the total score of QLICD-PU (P<0.05). Conclusion The detection rate of PU anxiety is high, and the combination of anxiety may aggravate the clinical symptoms such as abdominal distension, nausea and vomiting, and affect the quality of life of patients.

Key words Peptic Ulcer; Anxiety; Clinical Symptoms; Quality of life