Journal of International Psychiatry

Abstract: Objective To analyze the relationship between sleep disorders, depression, anxiety, nutritional status, and micro inflammation in elderly patients undergoing maintenance hemodialysis (MHD). Methods118 patients who underwent MHD were selected as the study subjects. The general data of patients were collected in the form of questionnaires and their early clinical data were collected through the electronic medical record database. Two of them were separated during the study. 118 patients were divided into sleep disorder group (n=70) and non sleep disorder group (n=48) according to whether there was sleep disorder. The sleep quality of elderly MHD patients and their negative emotions were analyzed.ResultsThe scores of SAS, SDS, MQSGA and the levels of parathyroid hormone (PTH) and C-reactive protein (CRP) in the sleep disorder group were higher than those in the non sleep disorder group, and the levels of serum albumin (ALB) were lower than those in the non sleep disorder group, with significant differences (P<0.05).Pearson correlation analysis showed that SAS score, SDS score, MQSGA score, PTH and CRP levels were positively correlated with the sleep quality of elderly MHD patients, while ALB was negatively correlated with the sleep quality of elderly MHD patients, with a statistically significant difference (P<0.05).Conclusion Severe depression, anxiety, low nutritional status, and micro inflammatory status are closely related to the occurrence of sleep disorders in elderly patients with MHD.

Key words: maintenance hemodialysis; Sleep disorders; Depression and anxiety; Nutritional status; Microinflammation