认知行为疗法应用于直肠癌新辅助放化疗患者的效果及对负面情绪与免疫功能的影响
Effects of cognitive behavioral therapy on negative emotions and immune function in patients with neoadjuvant chemoradiotherapy for rectal cancer
ES评分 0
| DOI |
| 刊名 |
Journal of International Psychiatry
|
| 年，卷(期) |
2023, 50(4) |
| 作者 |
|
| 作者单位 |
安阳市肿瘤医院重症医学科 ;
|
| 摘要 |
【摘要】目的：探究认知行为疗法对直肠癌新辅助放化疗患者负面情绪与免疫功能的影响。方法：选取2019年3月-2021年12月在我院就诊111例直肠癌新辅助放化疗患者,按随机数字表分为观察组(n=56)和对照组(n=55).对照组采用常规干预措施，观察组患者增加认知行为疗法，均持续干预1个月，对比两组患者自我护理能力、负面情绪、免疫功能、睡眠质量以及生活质量。结果：观察组自我概念、自我责任感、自我护理技能、自我护理知识等自我护理能力测量量表(ESCA)评分均高于对照组（P<0.05）；观察组汉密顿抑郁量表(HAMD)评分、汉密顿焦虑量表(HAMA)评分低于对照组（P<0.05）；观察组CD4﹢与CD4﹢/CD8﹢水平高于对照组，CD8﹢水平低于对照组（P<0.05）；观察组匹茨堡睡眠质量指数量表(PSQI)评分低于对照组，生活质量量表(QLQ-C30)评分高于对照组（P<0.05）。结论：认知行为疗法干预直肠癌新辅助放化疗患者，能够有效缓解患者负面情绪，提高自我护理能力，改善免疫功能，提高睡眠质量及生活质量，值得临床推广应用。
|
| Abstract |
[Abstract] Objective: To explore the effects of cognitive behavioral therapy on negative emotions and immune function in patients with neoadjuvant chemoradiotherapy for rectal cancer. Methods: A total of 111 patients with neoadjuvant chemoradiotherapy for rectal cancer in our hospital from March 2019 to December 2021 were selected and divided into observation group (n=56) and control group (n=55) according to random number table. The control group received conventional intervention measures, and the observation group received cognitive behavioral therapy for 1 month. The self-care ability, negative emotion, immune function, sleep quality and life quality of patients in the two groups were compared. Results: The ESCA scores of self-concept, self-responsibility, self-care skills and self-care knowledge in the observation group were higher than those in the control group (P<0.05). The scores of Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA) in observation group were lower than those in control group (P<0.05). The level of CD4+ and CD4+/CD8+ in the observation group was higher than that in the control group, while the level of CD8+ was lower than that in the control group (P<0.05). The PSQI score of the observation group was lower than that of the control group, and the QLQ-C30 score was higher than that of the control group (P <0.05). Conclusion: Cognitive behavioral therapy can effectively relieve negative emotions, improve self-care ability, improve immune function, and improve sleep quality and life quality in patients with rectal cancer neoadjuvant chemoradiotherapy, which is worthy of clinical application.
|
| 关键词 |
【关键词】 新辅助放化疗；直肠癌；认知行为疗法；负面情绪
|
| KeyWord |
【 Key words 】 neoadjuvant chemoradiotherapy; Rectal cancer; Cognitive behavioral therapy; Negative emotions
|
| 基金项目 |
|
| 页码 |
860-863 |
刘佳欣*.
认知行为疗法应用于直肠癌新辅助放化疗患者的效果及对负面情绪与免疫功能的影响 [J].
国际精神病学杂志.
2023; 50; (4).
860 - 863.