| Abstract |
[Abstract] Objective: To explore the effect of early hyperbaric oxygen therapy on the degree of depression and psychological resilience in patients with depression after hypertensive intracerebral hemorrhage. Method: Case data were collected and filed from January 2020 to December 2022. A total of 120 patients with depression after hypertensive intracerebral hemorrhage admitted to the hospital were included. The participants were divided into a control group (treated with conventional drugs) and an observation group (treated with conventional drugs and early hyperbaric oxygen) based on a 1:1 random number table method, with 60 patients included in each group; The depression degree, psychological resilience, neurological deficit, limb motor function and monoamine neurotransmitter level were observed and compared between the two groups. Result: Compared with the control group, the observation group had significantly lower scores on the 17 items Hamilton Depression Scale (HAMD-17) after 2 and 4 weeks of treatment (P<0.05); After treatment, the scores of the two groups on the Psychological Resilience Scale (CD-RISC) showed varying degrees of increase, and the increase was greater in the observation group (P<0.05); After intervention, the Fugl meyer motor function scale (FMA) scores of both groups increased, while the stroke scale (NIHSS) scores decreased, and the observation group was better (P<0.05); After treatment, the levels of norepinephrine (NE), 5-hydroxytryptamine (5-HT), and dopamine (DA) increased in both groups, and were even higher in the observation group (P<0.05). Conclusion: Hyperbaric oxygen therapy can effectively regulate the level of monoamine neurotransmitters, effectively improve the degree of depression in patients with depression after hypertensive intracerebral hemorrhage, improve neurological function and limb function, enhance their psychological resilience, and achieve a good prognosis
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