Journal of International Psychiatry

Objective The main purpose of this study is to evaluate the incidence of anxiety, depression and sleep problem in methamphetamine use disorder (MUD) patients, and the correlation with MUD. Method A total of 462 MUD patients and 312 healthy controls were included in this study. Anxiety, depression and sleep problem were assessed by Hamilton Anxiety Scale, Hamilton Depression Scale, and Pittsburgh Sleep Quality Index. Results The results showed that the incidence of anxiety, depression and sleep problem were higher in the MUD group than in the control (anxiety: 47.3 vs. 3.1%; depression: 50.2 vs. 2.1%; sleep problem: 62.0 vs. 31.7%), all P value <0.001. Multivariate logistic regression analysis indicated that MUD had higher risk of anxiety (OR=22.04，95%CI [8.75,55.49]), depression (OR=38.79，95%CI [13.11,114.76]), and sleep problem (OR=3.36，95%CI [2.25,5.02]) than the controls. Conclusion Individuals with MUD were more likely to have anxiety, depression and sleep problem, indicating that anxiety, depression and sleep problem should be assessed and treated during clinical interventions for MUD patients.

methamphetamine use disorder; anxiety; depression; sleep problem