International Journal of Surgical Research

Objective To analyze the effect of glucosamine hydrochloride capsule on knee osteoarthritis. Methods 104 patients with knee osteoarthritis were selected for research and analysis. The selected cases were from June 2021 to June 2022. They were randomly divided into two groups. 52 patients who were treated with nimesulide+omeprazole were set as the reference group, and 52 patients who were treated with glucosamine hydrochloride capsules on the above basis were set as the experimental group. The therapeutic effects of the two groups were compared. Results The effective rate of the experimental group was high (P<0.05). In the knee joint function score, there was no significant difference between the two groups before treatment, which could not meet the statistical significance (P>0.05). After treatment, it was higher in the experimental group (P<0.05). There was a significant increase after treatment in the group compared with that before treatment, and the difference was statistically significant (P<0.05). The incidence of adverse reactions was 5.77% in the experimental group and 19.23% in the reference group, which showed that the experimental group was relatively low (P<0.05). Conclusion Glucosamine hydrochloride capsule is effective in the treatment of knee osteoarthritis, which can promote the therapeutic effect of patients, improve their knee joint function, and has high therapeutic safety. This kind of treatment can be popularized in clinic.

Glucosamine hydrochloride capsules; Knee osteoarthritis; Effective rate of treatment; Knee joint function; Adverse reactions