Box-Behnken响应面法优化唐古特大黄有效成分的提取工艺

Optimization of extraction process of active components from Tanggu Radixby Box-Behnken response surface method

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DOI 10.12208/j.ijmd.20230036
刊名
International Journal of Medicine and Data
年,卷(期) 2023, 7(2)
作者
作者单位

青海师范大学生命科学学院 青海西宁;青海省青藏高原药用动植物资源重点实验室 青海西宁 ;
青海师范大学化学化工学院 青海西宁 ;

摘要
选取提取时间、粉碎粒度、乙醇体积分数、料液比四个单因素进行回流提取唐古特大黄总蒽醌的单因素实验,探究它们对唐古特大黄中有效成分含量的影响。再以单因素实验为基础,采取四因素三水平,对实验数据进行回归分析,最终得到最佳提取条件,为唐古特大黄后续的研究提供科学数据。
Abstract
Four single factors including extraction time, pulverization particle size, ethanol volume fraction and solid-liquid ratio were selected for reflux extraction of total anthraquinone in Tangutan Radix to explore their effects on the content of effective components in Tangutan Radix. Then, on the basis of single factor experiment, four factors and three levels were adopted to conduct regression analysis of experimental data, and finally the optimal extraction conditions were obtained, which provided scientific data for the subsequent research of Tanggu Radix Yellow.
关键词
回流提取;唐古特大黄;大黄素;Box-Behnken响应面设计法
KeyWord
reflux extraction; Tanggu super yellow; Emodin; Box-Behnken response surface design method
基金项目
页码 16-20
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吕秉遥*,李雪婷,韩鸿萍,陈志. Box-Behnken响应面法优化唐古特大黄有效成分的提取工艺 [J]. 国际医学与数据杂志. 2023; 7; (2). 16 - 20.

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