International Journal of Clinical Research

Objective: To investigate the effect of norepinephrine in total hip replacement in the elderly. Methods: A total of 108 elderly patients who underwent total hip arthroplasty in our hospital from January 2021 to January 2022 were selected as the subjects of this study. Based on the number of admission sequences of patients, 108 patients were randomly divided into control group and observation group by random number grouping. The control group was treated without norepinephrine; The observation group used norepinephrine. The incidence of perioperative adverse reactions in the control group and the observation group were compared. Perioperative fluid volume and mean arterial pressure and heart rate at different time points. Results: The incidence of adverse reactions in the perioperative period in the observation group; The perioperative infusion volume and mean arterial pressure and heart rate at different time points were significantly better than those in the control group, and the difference was statistically significant (P<0.05). Conclusion: The application of norepinephrine for elderly patients undergoing total hip arthroplasty can effectively reduce the incidence of perioperative adverse reactions, and at the same time improve the perioperative infusion volume and the average arterial pressure and heart rate at different time points, which has excellent effects in the process of practical application, which is worthy of further promotion and application.

Norepinephrine; Total hip replacement in the elderly; incidence of adverse reactions; mean arterial pressure and heart rate; Perioperative infusion volume