钙通道阻滞剂治疗高血压的临床评价与药理学简析

Clinical evaluation and pharmacological analysis of calcium channel blockers in the treatment of hypertension

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DOI 10.12208/j.ijcr.20230100
刊名
International Journal of Clinical Research
年,卷(期) 2023, 7(2)
作者
作者单位

重庆市奉节县中医院 重庆 ;

摘要
评价分析钙通道阻滞剂应用于高血压治疗中的价值与药理学作用。方法 选择我院2020年9月至2022年2月收治的原发性高血压病例80例,随机数字表法分为研究组、对照组,每组40例,对照组开展阿利沙坦酯给药,研究组联合给予钙通道阻滞剂治疗,连续用药6个月。评价两组患者治疗效果、血压与心率水平及治疗安全性。结果 治疗6个月后研究组治疗总有效率高于对照组,研究组血压、心率水平均低于对照组,差异均有统计学意义(P<0.05),两组患者治疗期间不良医学事件发生率比较无统计学差异(P>0.05)。结论 钙通道阻滞剂应用于高血压治疗中有助于提升疗效,控制血压与心率水平。
Abstract
Objective: To evaluate the value and pharmacological action of calcium channel blockers in the treatment of hypertension. Methods: A total of 80 cases of essential hypertension admitted to our hospital from September 2020 to February 2022 were randomly divided into study group and control group with 40 cases in each group. The control group was given alisartan ester, and the study group was given calcium channel blocker combined treatment for 6 months. The therapeutic effect, blood pressure, heart rate and safety of the two groups were evaluated. Results: After 6 months of treatment, the total effective rate of the study group was higher than that of the control group, and the blood pressure and heart rate of the study group were lower than that of the control group, with statistical significance (P < 0.05). There was no statistical difference in the incidence of adverse medical events between the two groups during treatment (P > 0.05). Conclusion: Calcium channel blocker in the treatment of hypertension is helpful to improve the curative effect and control the level of blood pressure and heart rate.
关键词
高血压;钙通道阻滞剂;药理学;血压;心率
KeyWord
Hypertension; Calcium channel blocker; Pharmacology; Blood pressure; Heart rate
基金项目
页码 174-177
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李良明*. 钙通道阻滞剂治疗高血压的临床评价与药理学简析 [J]. 国际临床研究杂志. 2023; 7; (2). 174 - 177.

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