Journal of Modern Nursing MedicineJPCNS

Objective To explore the effects of different decocting methods on the components of Maxing Shigan Decoction. Methods Different decocting methods were selected to prepare Maxing Shigan Decoction, and pseudoephedrine, fried dough twist alkaloid, glycyrrhizin, bitter almond and other components were obtained respectively. The contents obtained by different decocting methods were determined by HOLC method, and the metal elements were determined by ICP-ASE. Results Different decocting methods have some effects on the components of Maxing Shigan Decoction. The components of ephedrine and pseudoephedrine in ephedrine and ephedrine gypsum decocted first are significantly higher than those decocted together and decocted first, with statistical significance (P<0.05). Conclusion In order to ensure the efficacy, the best method is to decoct ephedra gypsum first, which can not only retain the drug properties to the maximum extent, but also facilitate the dissolution of trace elements in Maxing Shigan Decoction, so as to play a better clinical treatment effect.

Maxing Shigan Decoction; Pseudoephedrine; Fried dough twist base