International Journal of Medicine and Data

Objective To discuss the effect of papaverine on coronary spasm angina pectoris. Methods 76 patients with coronary spasm angina pectoris were randomly divided into two groups, 38 patients in each group. The control group was treated with conventional symptomatic treatment, and the treatment group was treated with papaverine on the basis of the control group. The total effective rate, incidence of angina pectoris, degree of angina pectoris pain and degree of myocardial injury were compared between the two groups. Results The total effective rate of the treatment group(94.74%)was significantly higher than that of the control group(78.95%), (P<0.05); Compared with the control group, the frequency of angina pectoris attack in the treatment group was significantly less, and the average attack time was significantly shorter(P<0.05);Compared with the control group, the attack of angina pectoris in the treatment group was milder(P<0.05);Compared with the control group, cardiac troponin I(cTnI)and creatine kinase isoenzyme(CK-MB)in the treatment group were significantly lower(P<0.05). Conclusion The addition of papaverine to the treatment of patients with coronary spasm angina pectoris after routine treatment can reduce the number and degree of angina pectoris, improve the symptoms of angina pectoris, shorten the onset time, help to promote recovery of patients, and the treatment effect is relatively significant.

Papaverine; Coronary spastic angina pectoris; Clinical efficacy