贝伐珠单抗靶向治疗联合TC化疗方案治疗晚期非小细胞肺癌的疗效观察

Targeted therapy of Bevacizumab combined with TC chemotherapy in the treatmentof advanced non-small cell lung cancer

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DOI 10.12208/j.ijcr.20230250
刊名
International Journal of Clinical Research
年,卷(期) 2023, 7(6)
作者
作者单位

武警甘肃省总队医院 甘肃兰州 ;

摘要
分析晚期非小细胞肺癌(NSCLC)采取贝伐珠单抗靶向治疗+TC化疗方案的效果。方法 选择2020年1月至2022年3月收治的晚期NSCLC患者80例,随机分为观察组(贝伐珠单抗靶向治疗+TC化疗)与对照组(TC化疗)各40例,对比治疗效果。结果 观察组肿瘤标志物水平、不良反应发生率、症状领域分数均低于对照组(P<0.05);观察组功能领域评分、治疗有效率、健康状况评分均高于对照组(P<0.05)。结论 贝伐珠单抗靶向治疗与TC化疗联合治疗晚期NSCLC可有效降低肿瘤标志物水平,改善生活质量,价值较高。
Abstract
Objective To analyze the effect of Bevacizumab Targeted therapy+TC chemotherapy regimen for advanced non-small cell lung cancer (NSCLC). Methods Eighty patients with advanced NSCLC admitted from January 2020 to March 2022 were randomly divided into the observation group (Bevacizumab Targeted therapy+TC chemotherapy) and the control group (TC chemotherapy), with 40 cases in each group. The therapeutic effects were compared. Results The levels of tumor markers, incidence of adverse reactions, and symptom domain scores in the observation group were lower than those in the control group (P<0.05); The functional domain scores, treatment effectiveness, and health status scores of the observation group were higher than those of the control group (P<0.05). Conclusion The combination of Bevacizumab Targeted therapy and TC chemotherapy in the treatment of advanced NSCLC can effectively reduce the level of tumor markers and improve the quality of life, with high value.
关键词
肿瘤标志物;晚期非小细胞肺癌;贝伐珠单抗靶向治疗;生活质量;TC化疗;不良反应
KeyWord
Tumor biomarkers; Advanced non-small cell lung cancer; Targeted therapy with Bevacizumab; Quality of life; TC chemotherapy; Adverse reactions
基金项目
页码 30-32
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赵文鹏*,李斌,张琼,李渊,周议朝. 贝伐珠单抗靶向治疗联合TC化疗方案治疗晚期非小细胞肺癌的疗效观察 [J]. 国际临床研究杂志. 2023; 7; (6). 30 - 32.

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